The Warwick Toxin Research Group is part of the Molecular Cell Biology Section in the Department of Biological Sciences at the University of Warwick.   Research is primarily focused on the cellular uptake, structure and mode of action of ricin and related ribosome inactivating proteins (RIPs). Housed within a top-rated research department, the Toxin Research Group has expertise in the following areas:

Studying the cellular entry of cytotoxins using cultured mammalian cells to elucidate novel transport
    pathways.

Exploiting the potency of these proteins by designing them as therapeutic agents, or using them as effective
    intracellular delivery vehicles.

Structure-function analysis of toxic proteins, including ricin and E. coli Shiga-like toxin 1.

Membrane translocation and protein refolding.

The biosynthesis and role of RIPs in plants.

Vacuolar targeting and secretion of RIPs in plant cells.